Introduction

The research directions of Ma Jianfeng's research group focuse on the additive manufacturing technology of dental ceramic, surface superhydrophobic modification technology, manufacturing technique and optimization of dental implants, and research of bone tissue substitute. The composition formula, additive manufacturing technique route, high-precision complex structure manufacturing and composite ceramic preparation of dental ceramics are studied in our group to achieve optimized mechanical properties and aesthetic effects for matching natural teeth in terms of flexural strength, fracture toughness, bond strength and light transmission; Superhydrophobic modification of natural tooth surface is studied here to reduce bacterial adhesion and plaque biofilm formation in saliva; Bioceramic materials and biodegradable metal materials are studied in dental implants and bone tissue engineering to achieve bone healing functions such as vascular regeneration, bone growth and bone integration.

Research field

1. Research and development of additive manufacturing technology for dental zirconia and lithium disilicate glass ceramics and preparation of high-precision complex structures;
2. Study on the anti-bacterial adhesion and anti-biofilm formation of superhydrophobic coatings on the surface of natural teeth;
3. Application of bioactive ceramics and biodegradable metals in dental implants and bone tissue engineering.
    

Principal

Ma jianfeng（doctor）archiater, School and Hospital of Stomatology Wenzhou Medical University, Principal of the research group

Personal Profile: Dr. Ma Jianfeng, engaged in oral health for more than 30 years, has carried out research and application of many core technologies such as precision attachments, all-porcelain prosthetics, and immediate implantation. He has made outstanding contributions to the treatment of various kinds of difficult and complicated oral prosthetics such as defects of teeth and dentition and loss of dentition, which has established the leading position of prosthodontics of Wenzhou Medical University in Wenzhou and Zhejiang Province. In teaching, Dr. Ma Jianfeng has built a diversified talent training system from undergraduate to master's, full-time to adult education, international students and students from Hong Kong, Macao and Taiwan. The major of Stomatology under the charge of Dr. Ma Jianfeng was approved as the dominant major of Zhejiang Province in 2016, the first-class undergraduate major construction site of Zhejiang Province in 2020, and the national first-class undergraduate major construction site in 2021. Dr. Ma Jianfeng insists on the combination of scientific research, teaching and clinical, and sticks to the clinical front line for a long time, so that Wenzhou oral prosthesis and implanting clinical treatment are in line with the advanced level at home and abroad. Over the past few years, Dr. Ma Jianfeng has actively participated in important conferences at home and abroad, participated in the compilation of national textbooks, participated in the compilation and edited 12 books. He obtained 8 national scientific research projects and the provincial research projects. He has published nearly 100 papers, including more than 30 SCI papers. He has presided over 4 National Natural Science Foundation projects, 5 provincial and ministerial level scientific research and teaching projects, won 2 provincial science and technology awards, 1 third prize of scientific research achievements of Zhejiang Provincial universities, and authorized 6 national invention patents and utility model patents; Selected in Zhejiang Province 151 talent project.

School and Hospital of Stomatology Wenzhou Medical University

Address: 268 Xueyuan West Road, Lucheng District, Wenzhou City, Zhejiang Province

e-mail: dentistmacn@aliyun.com

Member

Achievement

Representative papers:

1. Li Zhu , Xian Tong , Zengqi Ye , Zhiqiang Lin , Tianhong Zhou , Shengbin Huang , Yuncang Li , Jixing Lin , Cuie Wen , Jianfeng Ma. Zinc phosphate, zinc oxide, and their dual-phase coatings on pure Zn foam with good corrosion resistance, cytocompatibility, and antibacterial ability for potential biodegradable bone-implant applications[J]. Chemical Engineering Journal, 2022, 450: 137946.

2. Xinghai Wu , Cheng Wang , Jia Wang , Yuchen Feng , Yunpeng Zhu , Yijia Pan , Yifan Yuan , Chenhui Chen , Junyan Cao , Jixing Lin , Xian Tong , Yuncang Li , Cuie Wen , Xinkun Shen , Jianfeng Ma. Antiadhesive, antibacterial, and anti-inflammatory sandwich-structured ZIF8-containing gauze for enhanced wound healing[J]. Chemical Engineering Journal, 2024, 491: 152060.

3. Li Zhu , Yidi Xu , Siwen Liu , Huanhuan Chen , Jiyi Tao , Xian Tong , Yuncang Li , Shengbin Huang , Jixing Lin , Cuie Wen , Jianfeng Ma. Microstructure, mechanical properties, friction and wear performance, and cytotoxicity of additively manufactured zirconia-toughened alumina for dental applications[J]. Composites Part B: Engineering, 2023, 250: 110459.

4. Zengqi Ye , Li Zhu , Tianhong Zhou , Xian Tong , Zhaoping Chen , Xin Zhou , Shengbin Huang , Yuncang Li , Jixing Lin , Cuie Wen , Jianfeng Ma. Shear bond strength, finite element analysis, flexural strength and accuracy analysis of additively manufactured bio-inspired 3Y-TZP for dental applications[J]. Journal of Materials Research and Technology, 2024, 29: 4588-4596.

5. Xin Zhou , Yixuan Luo , Xian Tong , Li Zhu , Yihao Wu , Jixing Lin , Shengbin Huang , Jianfeng Ma. Superhydrophobic PDMS/SiNPs/T-ZnOw coating with reduced adhesion of Streptococcus mutans for dental caries prevention[J]. Ceramics International, 2023, 49(4): 6228-6237.

6. Xian Tong, Li Zhu, Yihao Wu, Yiting Song, Kun Wang, Shengbin Huang, Yuncang Li, Jianfeng Ma, Cuie Wen, Jixing Lin. A biodegradable Fe/Zn–3Cu composite with requisite properties for orthopedic applications[J]. Acta Biomaterialia, 2022, 146: 506-521.

7. Xian Tong, Hongning Wang, Li Zhu, Yue Han, Kun Wang, Yuncang Li,Jianfeng Ma, Jixing Lin, Cuie Wen, Shengbin Huang. A biodegradable in situ Zn–Mg2Ge composite for bone-implant applications[J]. Acta Biomaterialia, 2022, 146: 478-494.

8. Xian Tong, Yilong Dong, Runqi Zhou, Xinkun Shen, Yuncang Li, Yue Jiang, Huiyuan Wang, Jinguo Wang, Jixing Lin, Cuie Wen. Enhanced Mechanical Properties, Corrosion Resistance, Cytocompatibility, Osteogenesis, and Antibacterial Performance of Biodegradable Mg–2Zn–0.5 Ca–0.5 Sr/Zr Alloys for Bone‐Implant Application[J]. Advanced Healthcare Materials, 2024, 13(12): 2303975.

9. Yue Han, Xian Tong, Runqi Zhou, Yilin Wang, Yuge Chen, Liang Chen, Xinhua Hong, Linmei Wu, Zhiqiang Lin, Yichi Zhang, Xuejia Zhang, Chaoming Hu, Bin Li, Yifan Ping, Zelin Cao, Zhou Ye, Zhongchen Song, Yuncang Li, Cuie Wen, Yongsheng Zhou, Jixing Lin, Shengbin Huang. Biodegradable Zn‐5Dy Alloy with Enhanced Osteo/Angio‐Genic Activity and Osteointegration Effect via Regulation of SIRT4‐Dependent Mitochondrial Function[J]. Advanced Science, 2024, 11(13): 2307812.

10. Xian Tong, Yue Han, Runqi Zhou, Wanying Jiang, Li Zhu, Yuncang Li, Shengbin Huang, Jianfeng Ma, Cuie Wen, Jixing Lin. Biodegradable Zn–Dy binary alloys with high strength, ductility, cytocompatibility, and antibacterial ability for bone-implant applications[J]. Acta Biomaterialia, 2023, 155: 684-702.

11. Xian Tong, Li Zhu, Kun Wang, Zimu Shi, Shengbin Huang, Yuncang Li, Jianfeng Ma, Cuie Wen, Jixing Lin. Impact of gadolinium on mechanical properties, corrosion resistance, and biocompatibility of Zn-1Mg-xGd alloys for biodegradable bone-implant applications[J]. Acta Biomaterialia, 2022, 142: 361-373.

12. Tianhong Zhou, Li Zhu, Xiaonan Luo, Jiancheng Yu, Chuchu Ye, Xin Zhou, Xian Tong, Zhaoping Chen, Yuncang Li, Jixing Lin, Cuie Wen, Jianfeng Ma. Effects of external staining on mechanical, optical, and biocompatibility properties of additively manufactured 3Y-TZP ceramic for dental applications[J]. Journal of Materials Research and Technology, 2024, 31: 3961-3970.

13. Xian Tong, Quanxiang Sun, Dechuang Zhang, Kun Wang, Yilong Dai, Zimu Shi, Yuncang Li, Matthew Dargusch, Shengbin Huang, Jianfeng Ma, Cuie Wen, Jixing Lin. Impact of scandium on mechanical properties, corrosion behavior, friction and wear performance, and cytotoxicity of a β-type Ti–24Nb–38Zr–2Mo alloy for orthopedic applications[J]. Acta Biomaterialia, 2021, 134: 791-803.

Monograph:

1. 麻健丰，安厚鹏，邓婧，吴建斌，《口腔科学》2013年，麻健丰主编，人民军医出版社。

2. 周延民，陈吉华，《口腔医学 口腔修复学分册》2016年，麻健丰副主编，人民卫生出版社。

3. 姚江武，麻健丰，《口腔修复学分册》第三版，麻健丰主编，人民卫生出版社。

4. 李长义，《固定义齿工艺技术》第二版，麻健丰编者，人民卫生出版社。

Patent:

1. Process removal massager (Authorization Number: ZL201210267954.X).

2. Toothbrush process removal massager (Authorization Number:ZL201210267788.3).

3. Gel injection molding method of zirconia toughened alumina dental ceramic based crown (Authorization Number:ZL200910099256.1)

4. The invention relates to a biodegradable metal skeleton reinforced Zn matrix composite with large area galvanic corrosion structure (Authorization Number:ZL202111324382.X)

5. The invention discloses a biomimetic enamel material and a method for making biomimetic teeth (Authorization Number:ZL201810647361.3)

6. The invention relates to an X-type medical sleeve crown extractor suitable for oral repair (Authorization Number:ZL201420587318.X)

7. The invention relates to a superhydrophobic gel nano-coating for inhibiting bacterial adhesion and a preparation method thereof (Authorization Number:ZL201911134309.9)

8. Preparation method of porous zinc biocomposite coating for degradable bone scaffolds (Authorization Number:ZL202111170985.9)

9. The invention relates to a method for preparing biodegradable Mo-Cu-X biomedical material (Authorization Number:ZL2021111863014)

10. A gradient bionic dental ceramic (Authorization Number:ZL2021116088281)

11. Degradable in-situ authigenic Mg2Ge particle reinforced Zn matrix composite and a preparation method thereof (Authorization Number:ZL2022100538894)

12. The invention relates to a preparation method of degradable zinc powder metallurgical biomedical material coated with phosphate biological coating (Authorization Number:ZL2023102316915)

13. The invention relates to the refining of degradable Zn-Mg2Ge composite material by combination of ultrasonic wave and modifier and a preparation method thereof (Authorization Number:ZL2022103849467)

Project

1. Ma jianfeng，Zhejiang Province 'Sharp and Leading Goose' Major Science and Technology Project，2021-2024，1 millions

2. Ma jianfeng，National Natural Science Foundation of China，2023-2026, 0.48 millions

3. Ma jianfeng，Major Science and Technology Innovation Project of Wenzhou City，2023-2026, 1 millions
4. Zhu li，National Natural Science Foundation of China Youth Science Fund Project，2024-2027，0.3 millions

5. Zhu li，Zhejiang Province Basic Public Welfare Research Program，2023-2026，0.1 millions

6. Lin jixing，Zhejiang Province Basic Public Welfare Research Program，2022-2025，0.1 millions

7. Tong xian，Zhejiang Province Basic Public Welfare Research Program ，2024-2027，0.1 millions

Contact us

Introduction to the research group：
Research group Leader: Ma Jianfeng, archiater, doctoral supervisor. In the past 3 years, he has presided over a number of scientific research projects such as the National Natural Science Foundation of China and Zhejiang Province 'Sharp and Leading Goose' Major Science and Technology Project. At present, the research group has 3 researchers, associate researchers and assistant researchers, 4 doctors and 13 masters. The research group mainly focus on the application of ceramics, dental implants and bioactive materials for dental bone defects based on additive manufacturing processes, and explore the directions of additive manufacturing processes, superhydrophobic modification of natural tooth enamel surface, bone integration of dental implants, and bone tissue engineering of oral and maxillofacial bone defects.

Basic research direction：

1. Research and development of additive manufacturing technology for dental zirconia and lithium disilicate glass ceramics and preparation of high-precision complex structures.

2. Study on the anti-bacterial adhesion and anti-biofilm formation of superhydrophobic coatings on the surface of natural teeth.

3. Application of bioactive ceramics and biodegradable metals in dental implants and bone tissue engineering.

Applied research direction：

1. Preparation of extremely thin and strong ceramic for minimally invasive/non-invasive dental restoration.