中文

**Research Group Overview**

The research direction of Professor Hu Rongdang's group mainly focuses on the study of impacted tooth correction, the biomechanics of orthodontic correction, and the application of nanomaterials in the treatment of oral and systemic diseases. Particularly, in-depth research has been conducted on the clinical studies and therapeutic mechanisms of various types of impacted teeth, as well as on the growth and development of the craniofacial region. The clinical technology related to impacted teeth has been recognized as one of the first batch of advanced new clinical technologies and projects at the international level by Wenzhou Medical University.

**Research Areas**

1. Research and orthodontic treatment of developmental abnormalities and deformities in children's teeth and jaws;

2. Study of the mechanics of tooth movement;

3. Prevention of dental caries during orthodontic treatment;

4. Clinical research on morphology and treatment of various types of impacted teeth;

5. Research on the use of nanoprodrugs encapsulated by E. coli membranes for the treatment and immunomodulation of bacterial infections;

6. Application and research of nanohydrogels in the repair of diabetic wounds;

7. Mechanism study of periodontal disease and cardiovascular disease.

**Head of the Group**

Professor Hu Rongdang, a chief physician and doctoral supervisor, is also the vice chairman of the Wenzhou Municipal Committee of the Chinese People's Political Consultative Conference (CPPCC) and the leader of the Wenzhou Committee of the China Democratic League (CDL).

**Personal Profile**

Dr. Hu Rongdang, chief physician, professor, and doctoral supervisor in oral medicine, received his bachelor’s degree from the School of Stomatology at Zhejiang University, his master’s degree from the School of Stomatology at Wuhan University, and his doctorate from the School of Stomatology at Tongji University. He is a fellow of the International College of Dentists and a member of the Royal College of Surgeons of Edinburgh (Dental Surgery). He has been a visiting scholar at the University of Edinburgh Dental School, University of Washington School of Dentistry, and Loma Linda University School of Dentistry. He is a member of the Central Committee of the China Democratic League and the leader of the Wenzhou Committee of the China Democratic League, as well as the vice chairman of the 12th CPPCC of Wenzhou. He is an editorial board member of the national unified undergraduate textbook "Orthodontics" published by the People's Medical Publishing House, the chief editor of the national unified vocational college textbook "Aesthetic Medicine of Stomatology," and an editorial board member of the "Chinese Journal of Orthodontics." He is also a standing committee member of the Orthodontics Professional Committee of the Chinese Stomatological Association, a member of the Sleep Expert Committee of the Chinese Physician Association, and a member of the Medical Education Committee of the Chinese Stomatological Association. He is also the deputy director of the Zhejiang Province Orthodontics Professional Committee, a member of the Zhejiang Province Medical Education Committee, a member of the Zhejiang Province Medical Aesthetics and Beauty Special Committee, the vice president of the Wenzhou City Stomatological Society, an expert in medical accident technology identification of the Wenzhou City Medical Association, a training target of the "551 Talent Project" of Wenzhou City, and an outstanding alumnus of Zhejiang University School of Medicine. His main research focuses on orthodontic techniques, basic and applied research in oral biomechanics, especially in clinical research and therapeutic mechanisms of various types of impacted teeth and craniofacial growth and development. He comprehensively conducts growth modification of abnormal craniofacial development in children, orthodontic correction of malocclusions in children and adults, and oral appliance treatment of obstructive sleep apnea syndrome. The related clinical technology for impacted teeth has been recognized as one of the first batch of advanced new clinical technologies and projects at the international level by Wenzhou Medical University.

**Members**

The group includes several researchers including postgraduates Chen Siyun, Xu Hangbin, He Wei, Xu Shengming, Huang Wenxinyu, and Tu Congyi.

**Representative Publications in Recent Years**

1. Chi J, Yan L, Chen S, Zhou J, Voliere G, Pan W, Gong Y, Lin H, Hu R. Factors affecting local alveolar bone thickness in unilateral maxillary canine-lateral incisor transposition. Am J Orthod Dentofacial Orthop. 2024 May;165(5):576-585.

2. Hu H, Hu R, Wu G, Sun C. The evaluation of lateral incisor adjacent to treated labial inversely impacted maxillary central incisor: A retrospective follow-up study. Am J Orthod Dentofacial Orthop. 2023;164(1):57-66.

3. Mu Z, Jin T, Chu T, Lu H, Chen Y, Li S, Zeng B, Huang C, Lei K, Cai X, Deng H, Hu R. Functionalized MoS2-nanosheets with NIR-Triggered nitric oxide delivery and photothermal activities for synergistic antibacterial and regeneration-promoting therapy. J Nanobiotechnology. 2023 Dec 4;21(1):463.

4. Du W, Chi J, He S, Wu G, Pan W, Wang Y, Voliere G, Hu R. The position and morphology characteristics of multiple impacted anterior teeth in the unilateral maxillary area: A retrospective study based on cone-beam computed tomography. Am J Orthod Dentofacial Orthop. 2022 Dec;162(6):907-916.

5. Sun X, He, Zhu Y, Obeng Enoch, Zeng B, Deng H, Shen J, Hu R. Valence-switchable and biocatalytic vanadium-based MXene nanoplatform with photothermal-enhanced dual enzyme-like activities for anti-infective therapy. CHEM ENG J 2023; 451(4);138985.

**Monographs in Chinese**

1. "Aesthetic Medicine of Stomatology" (2021), edited by Yu Haiyang and Hu Rongdang, published by the People's Medical Publishing House.

**Patents Applied For**

1. June 10, 2022: Application and preparation method of mesoporous silica-loaded nitrogen-doped graphene nanocomposites in the preparation of photothermal therapy drugs for periodontitis.

2. February 2, 2021: A device for expanding dental gaps.

3. September 2, 2019: An auxiliary clamping device for bonding invisible orthodontic attachments.

4. March 15, 2019: A dental occlusal pad that reduces bacterial adhesion rate.

5. March 15, 2019: An improved occlusal pad type removable orthodontic appliance.

6. April 1, 2016: A device for restoring and maintaining the space after the loss of primary teeth.

**Projects Hosted by the Group in Recent Three Years**

1. Professor Hu Rongdang, funded by the Natural Science Foundation of Zhejiang Provincial Department of Science and Technology, 2023-2025, 100,000 RMB.

2. Professor Hu Rongdang, funded by the Wenzhou Municipal Science and Technology Bureau for a major scientific and technological innovation project in Wenzhou, 2020-2024, 500,000 RMB.