The Institute of Oral Science, School &Hospital of Stomatology, formerly known as the Dental Materials Lab and Orthodontic Lab, was founded in December 2002. In October, 2012, the Institute of Oral Science was established. The new institute is composed of Oral biomaterial lab 1, Oral biomaterial lab 2, Oral cell biology lab, Oral molecular biology lab and the newly-built Oral Science lab of Biomedical Scientific Research Building, Wenzhou Medical University. Up to 2016, the laboratory now has occupied an area of 690 square meters with research instruments worth more than ￥8.5 million.The main research directions of our institute cover the development and application of novel oral restorative materials, the research of mechanisms and related drugs in oral common diseases, the research of dental tissue engineering and regenerative medicine, the research of dental implantable instruments and the fabrication and development of oral drug controlled-release system. As a public medical lab, the Institute serves not only for the staff and postgraduates’ research items and social research projects, but also bears the undergraduates' extracurricular academic research. During the past four years, we have been in charge of 36 projects including 7 national foundation projects, 14 provincial foundation projects and 15 municipal foundation projects. All together, our institute has about 3.9 million research funds. The staffs of our institute have published over 94 articles as the first author and the corresponding author and 53 papers of them were published in SCI journals. We have 9 authorized patents. Under the general editorship of our staffs, we have compiled 4 teaching material of Dentistry. In addition, we have developed widely cooperation with domestic and international universities in scientific research, for example University of the Pacific (US), the Loma Linda University (US), University of Amsterdam (Holland) and James Cook University (Australia), etc.